anguish in WordNet English dictionary

1. extreme mental distress
   anguish  torment  torture 
   
2. extreme distress of body or mind
   anguish 
   

1. cause emotional anguish or make miserable
   "It pains me to see my children not being taught well in school"
   pain  anguish  hurt 
   
2. suffer great pains or distress
   anguish