depart in WordNet English dictionary

1. go away or leave
   depart  take leave  quit 
   
2. leave
   "The family took off for Florida"
   depart  part  start  start out  set forth  set off  set out  take off 
   
3. wander from a direct or straight course
   sidetrack  depart  digress  straggle 
   
4. move away from a place into another direction
   "Go away before I start to cry"; "The train departs at noon"
   go  go away  depart 
   
5. remove oneself from an association with or participation in
   "She wants to leave"; "The teenager left home"; "She left her position with the Red Cross"; "He left the Senate after two terms"; "after 20 years with the same company, she pulled up stakes"
   leave  depart  pull up stakes 
   
6. be at variance with; be out of line with
   deviate  vary  diverge  depart