thickened in WordNet English dictionary

1. having calluses; having skin made tough and thick through wear
   "calloused skin"; "with a workman's callous hands"
   calloused  callous  thickened 
   
2. made or having become thick
   "thickened bronchial arteries"
   thickened 
   
3. made thick in consistency
   "flour-thickened gravy"; "dust-thickened saliva"
   thickened