vexation in WordNet English dictionary

1. the act of troubling or annoying someone
   annoyance  annoying  irritation  vexation 
   
2. anger produced by some annoying irritation
   annoyance  chafe  vexation 
   
3. the psychological state of being irritated or annoyed
   irritation  annoyance  vexation  botheration 
   
4. something or someone that causes anxiety; a source of unhappiness
   "New York traffic is a constant concern"; "it's a major worry"
   concern  worry  headache  vexation